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Edward H. Abraham


Edward H. Abraham

Oklahoma Surgical Hospital, USA

Biography

Edward H. Abraham graduated from Harvard University with a college major in engineering, applied physics and chemistry. He was then accepted into the first class of the Harvard - MIT graduate program in Health Sciences and Technology and subsequently received his MD from Harvard Medical School. During his medical school training, he gained valuable research experience working in the laboratories of Professors Judah Folkman, Claude Lechene and Nobel Laureate Konrad Bloch. During his internship, residency and fellowship in pediatrics at Boston Children’s HospitalMedical Center, he worked directly with Professor Harry Shwachman and in the laboratory of Professor Jan Breslow focusing on cystic fibrosis (CF). He extended his CF studies with a subsequent post-doctoral research clinical investigator award from NIH. His work focused on membrane biochemistry in the laboratory of Professor Guido Guidotti at Harvard University. During these investigations, he discovered and investigated functions of ATP releasing pathways using biochemical and electrophysiological (patch-clamp) assays. He developed luciferase assays for precise measurement and imaging of extracellular ATP clouds. Dr. Abraham then completed a radiation oncology residency at Massachusetts General Hospital, Boston and subsequent Senior Investigator position with Dr. Paul Okunieff at the National Cancer Institute (NCI) where the role of extracellular ATP in cancer treatment was investigated. He subsequently assumed directorship of the Radiation Oncology Translational Research laboratory at Dartmouth Medical School in Hanover, NH. At Dartmouth he ran clinical trials testing the effects of ATP intravenous infusions on patients with stage IV cancers

Abstract

Abstract : Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARSCoV-2